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Harald Huber (at far left)
and research team

University of Regensburg




The phylogeny of 16S ribosomal RNA
The archaeal hyperthermophiles occupy the basal root of the tree of life, strongly suggesting that they were the original form of life on this planet.




The Regensburg "Witches' Kitchen"
To culture hyperthermophiles requires the construction of laboratory equipment capable of maintaining volcanic conditions in the laboratory.




Woods Hole deep sea submersible
The volcanic biotopes of the hyperthermophiles are among the most extreme on earth, often requiring elaborate equipment to reach, although they are also found in continental solfataric areas, requiring nothing more elaborate than a strong pair of boots and some nerve.








July 24, 2006

Part X: Astrobiology

Hyperthermophilic Microorganisms —
A Possibility for Extraterrestrial Life?

Harald Huber, University of Regensburg
29 min. (slideshow requires QCShow Player)
Audio only (mp3 format)
View as a webpage (quicktime, real player) (notes)

What is accomplished by fire is alchemy — whether in the furnace or in the kitchen stove. And he who governs fire is Vulcan, even if he be a cook or a man who tends the stove.
— Paracelsus, 1493-1541

Thirty years ago it was commonly stated in textbooks that no organic (carbon-based) life could survive at temperatures greater than 70°C, and that pasteurization would be complete at 80°C.

In the intervening decades, we've since discovered life on this planet that cannot survive at temperatures lower than 80°C, with many species of hyperthermophilic archaea having their optimal growth temperatures greater than that of boiling water. One recently discovered species, Pyrolobus fumerii, reaches its upper temperature limit at an astounding 121°C, a temperature at which protein denaturization would have previously been assumed to be complete.

Hyperthermophilic microorganisms are defined to be those organisms that their exhibit optimal growth temperatures above 80°C and represent the upper temperature border of life on our planet. They thrive in continental solfataric (volcanic sulfurous steam) regimes and submarine hydrothermal systems, where they form complex communities.

Hyperthermophiles are highly diverse in their morphologies and metabolic properties. Most are anaerobes which use inorganic redox reactions as energy sources, conditions reminiscent of the earliest Earth. These properties enable them to grow in the absence of sunlight. They are also the most primitive organisms known so far.

In this talk, Harald Huber introduces a nano-sized symbiont/parasite, obtained from a submarine hydrothermal system, representing a new kingdom of Archaea, the "Nanoarchaeota." These organisms are only 400 nm in diameter (in the range of large viruses). "N. equitans" exhibits a genome size of only 490 kb, one of the smallest genomes known so far, thus it offers the possibility of providing extraordinary insights into the evolution of thermophily, of the minimal genetic equipment of cells, and of inter-species communications. Almost no genes for metabolism or biosynthesis could be detected within its genome, which further argues for its status as a symbiont or parasite.

This talk was presented at the 2004 Astrobiology Science Conference in a large tent on the NASA Ames Research Center's grounds. The landing pattern for the adjacent Moffet Federal Airfield that day had the aircraft descending directly over the tent, thus you'll hear a number of jet aircraft landing during Harald's talk.

— Wirt Atmar


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